This 13-night Regent Seven Seas itinerary links Civitavecchia (Rome) to Santorini, threading 8 ports of call through 5 countries with 3 days at sea to unwind aboard Regent Seven Seas Mariner.
Why sail this route
You unpack once and let the ship do the travelling: 5 countries over 13 nights, starting in Civitavecchia (Rome) and finishing in Santorini, with a new port waiting most mornings instead of airports and hotel check-ins.
The pacing runs to 8 port days and 3 days at sea — time to enjoy the ship between stops.
Good to know
- Best for
- Repositioning & bucket-list cruisers
- Season
- Autumn sailing
- Route
- Civitavecchia (Rome) → Santorini
- Pace
- 8 port days · 3 sea days
Day-by-Day Itinerary
Hover a day to find it on the map.
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The Ship
Your home for all 13 nights aboard Regent Seven Seas Mariner — so you unpack once and wake up somewhere new each morning.
About This Cruise
The 13 Night Isles In Autumn Rome (Civitavecchia) To Athens (Piraeus) is a 13-night one-way itinerary aboard Regent Seven Seas Mariner. You board in Civitavecchia (Rome) and disembark in Santorini, calling at 8 ports across 5 countries along the way.
In sequence the voyage takes in Italy (Civitavecchia, Naples), Tunisia (Tunis), Malta (La Valletta), Croatia (Dubrovnik), Italy (Bari, Bari) and Greece (Corfu, Corfu, Santorini and 1 more).
As a one-way sailing you'll fly into Civitavecchia (Rome) and home from Santorini, so it's worth checking the two gateways before you book. Longer hops are crossed on the 3 days at sea, keeping daylight hours for the ports. Sailing dates, cabin availability and fares vary by season — use Check Dates & Prices for live pricing, or call our team to talk through the options.