This 16-night MSC itinerary links Livorno (Florence/Pisa) to La Romana, threading 8 ports of call through 8 countries with 9 days at sea to unwind aboard MSC Opera.
Why sail this route
You unpack once and let the ship do the travelling: 8 countries over 16 nights, starting in Livorno (Florence/Pisa) and finishing in La Romana, with a new port waiting most mornings instead of airports and hotel check-ins.
The pacing runs to 8 port days and 9 days at sea — time to enjoy the ship between stops.
Good to know
- Best for
- Repositioning & bucket-list cruisers
- Season
- Autumn sailing
- Route
- Livorno (Florence/Pisa) → La Romana
- Pace
- 8 port days · 9 sea days
Day-by-Day Itinerary
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The Ship
Your home for all 16 nights aboard MSC Opera — so you unpack once and wake up somewhere new each morning.
About This Cruise
The 16 Night MSC Grand Voyages is a 16-night one-way itinerary aboard MSC Opera. You board in Livorno (Florence/Pisa) and disembark in La Romana, calling at 8 ports across 8 countries along the way.
In sequence the voyage takes in Italy (Livorno), France (Marseille), Spain (Barcelona), Morocco (Tangier), Antigua (St Johns), St. Maarten (Philipsburg) and 2 more.
As a one-way sailing you'll fly into Livorno (Florence/Pisa) and home from La Romana, so it's worth checking the two gateways before you book. Longer hops are crossed on the 9 days at sea, keeping daylight hours for the ports. Sailing dates, cabin availability and fares vary by season — use Check Dates & Prices for live pricing, or call our team to talk through the options.