This 17-night MSC itinerary links Genoa to La Romana, threading 14 ports of call through 12 countries with 10 days at sea to unwind aboard MSC Opera.
Why sail this route
You unpack once and let the ship do the travelling: 12 countries over 17 nights, starting in Genoa and finishing in La Romana, with a new port waiting most mornings instead of airports and hotel check-ins.
The pacing runs to 14 port days and 10 days at sea — time to enjoy the ship between stops.
Good to know
- Best for
- Repositioning & bucket-list cruisers
- Season
- Autumn sailing
- Route
- Genoa → La Romana
- Pace
- 14 port days · 10 sea days
Day-by-Day Itinerary
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The Ship
Your home for all 17 nights aboard MSC Opera — so you unpack once and wake up somewhere new each morning.
About This Cruise
The 17 Night MSC Grand Voyages is a 17-night one-way itinerary aboard MSC Opera. You board in Genoa and disembark in La Romana, calling at 14 ports across 12 countries along the way.
In sequence the voyage takes in Italy (Genoa, Livorno), France (Marseille), Spain (Barcelona), Morocco (Tangier), Antigua (St Johns), St. Maarten (Philipsburg) and 2 more, among others.
As a one-way sailing you'll fly into Genoa and home from La Romana, so it's worth checking the two gateways before you book. Longer hops are crossed on the 10 days at sea, keeping daylight hours for the ports. Sailing dates, cabin availability and fares vary by season — use Check Dates & Prices for live pricing, or call our team to talk through the options.