Holland America · 21-Night Voyage

21 Night Eastern Caribbean & Panama Canal: U.S. Virgin Islands

21 NightsFort Lauderdale → San Juan10 Ports of Call8 Sea DaysAboard Holland America Nieuw Amsterdam

A 21-night one-way voyage aboard Holland America Nieuw Amsterdam, sailing from Fort Lauderdale to San Juan. It calls at 10 ports of call across 10 countries — Florida, Antigua, British Virgin Islands, Puerto Rico and 6 more, with 8 days at sea. Departs January 29, 2027.

The Voyage · Interactive Map
Port of call Sailing route
1 4 6 7 11 14 16 17 18 20
Drawn to scale from real coastline data — hover any port to explore it.

This 21-night Holland America itinerary links Fort Lauderdale to San Juan, threading 10 ports of call through 10 countries with 8 days at sea to unwind aboard Holland America Nieuw Amsterdam.

21Nights
10Ports
8Sea Days
Fort LauderdaleRound-Trip

Why sail this route

You unpack once and let the ship do the travelling: 10 countries over 21 nights, starting in Fort Lauderdale and finishing in San Juan, with a new port waiting most mornings instead of airports and hotel check-ins.

The pacing runs to 10 port days and 8 days at sea — time to enjoy the ship between stops.

Good to know

Best for
Grand-voyage & long-cruise travellers
Season
Winter sailing
Route
Fort Lauderdale → San Juan
Pace
10 port days · 8 sea days

Day-by-Day Itinerary

Hover a day to find it on the map.

  1. Day1
    Florida
    Fort Lauderdale Departs 4:00 PM
    Explore Fort Lauderdale
  2. Day2
    At Sea
    A Day at Sea
  3. Day3
    At Sea
    A Day at Sea
  4. Day4
    Antigua
    St Johns 9:00 AM – 6:00 PM
    Explore St Johns
  5. Day5
    Antigua
    St Johns 8:00 AM – 11:00 PM
    Explore St Johns
  6. Day6
    British Virgin Islands
    Tortola 8:00 AM – 6:00 PM
    Explore Tortola
  7. Day7
    Puerto Rico
    San Juan 8:00 AM – 5:00 PM
    Explore San Juan
  8. Day8
    At Sea
    A Day at Sea
  9. Day9
    Puerto Rico
    San Juan 8:00 AM – 3:00 PM
    Explore San Juan
  10. Day10
    Florida
    Fort Lauderdale 7:00 AM – 4:00 PM
    Explore Fort Lauderdale
  11. Day11
    Bahamas
    Half Moon Cay 8:00 AM – 5:00 PM
    Explore Half Moon Cay
  12. Day12
    At Sea
    A Day at Sea
  13. Day13
    At Sea
    A Day at Sea
  14. Day14
    Aruba
    Oranjestad 8:00 AM – 5:00 PM
    Explore Oranjestad
  15. Day15
    At Sea
    A Day at Sea
  16. Day16
    Colombia
    Cartagena 7:00 AM – 2:00 PM
    Explore Cartagena
  17. Day17
    Panama
    Colon 5:00 PM – 9:00 PM
    Explore Colon
  18. Day18
    Costa Rica
    Puerto Limon 7:30 AM – 4:30 PM
    Explore Puerto Limon
  19. Day19
    At Sea
    A Day at Sea
  20. Day20
    Grand Cayman
    George Town 7:00 AM – 4:00 PM
    Explore George Town
  21. Day21
    At Sea
    A Day at Sea
  22. Day22
    Grand Cayman · Disembark
    George Town Arrives 7:00 AM
    Explore George Town

The Ship

Holland America Nieuw Amsterdam
66.5
SCORE
Your floating hotel
Holland America Nieuw Amsterdam

Your home for all 21 nights aboard Holland America Nieuw Amsterdam — so you unpack once and wake up somewhere new each morning.

2010Launched
86,273Gross Tons
285.2 mLength
2,106Guests
874Crew
12Decks
OnboardCasino·Spa & Thermal Suite
View full Holland America Nieuw Amsterdam spec sheet & deck plans

About This Cruise

The 21 Night Eastern Caribbean & Panama Canal: U.S. Virgin Islands is a 21-night one-way itinerary aboard Holland America Nieuw Amsterdam. You board in Fort Lauderdale and disembark in San Juan, calling at 10 ports across 10 countries along the way.

In sequence the voyage takes in Florida (Fort Lauderdale), Antigua (St Johns, St Johns), British Virgin Islands (Tortola), Puerto Rico (San Juan, San Juan), Florida (Fort Lauderdale), Bahamas (Half Moon Cay) and 2 more, among others.

As a one-way sailing you'll fly into Fort Lauderdale and home from San Juan, so it's worth checking the two gateways before you book. Longer hops are crossed on the 8 days at sea, keeping daylight hours for the ports. Sailing dates, cabin availability and fares vary by season — use Check Dates & Prices for live pricing, or call our team to talk through the options.

From · per person
See live pricing
Check Dates