This 21-night Holland America itinerary links Piraeus (Athens) to Barcelona, threading 16 ports of call through 9 countries with 5 days at sea to unwind aboard Holland America Oosterdam.
Why sail this route
You unpack once and let the ship do the travelling: 9 countries over 21 nights, starting in Piraeus (Athens) and finishing in Barcelona, with a new port waiting most mornings instead of airports and hotel check-ins.
The pacing runs to 16 port days and 5 days at sea — time to enjoy the ship between stops.
Good to know
- Best for
- Grand-voyage & long-cruise travellers
- Season
- Spring sailing
- Route
- Piraeus (Athens) → Barcelona
- Pace
- 16 port days · 5 sea days
Day-by-Day Itinerary
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The Ship
Your home for all 21 nights aboard Holland America Oosterdam — so you unpack once and wake up somewhere new each morning.
About This Cruise
The 21 Night Greek Isles With Istanbul, Dubrovnik, Italy & Spain is a 21-night one-way itinerary aboard Holland America Oosterdam. You board in Piraeus (Athens) and disembark in Barcelona, calling at 16 ports across 9 countries along the way.
In sequence the voyage takes in Greece (Piraeus), Turkey (Kusadasi, Istanbul), Greece (Mykonos), Crete (Chania), Greece (Katakolon), Albania (Sarande) and 2 more, among others.
As a one-way sailing you'll fly into Piraeus (Athens) and home from Barcelona, so it's worth checking the two gateways before you book. Longer hops are crossed on the 5 days at sea, keeping daylight hours for the ports. Sailing dates, cabin availability and fares vary by season — use Check Dates & Prices for live pricing, or call our team to talk through the options.