This 7-night MSC itinerary links Piraeus (Athens) to Santorini, threading 6 ports of call through 2 countries with 1 day at sea to unwind aboard MSC Orchestra.
Why sail this route
You unpack once and let the ship do the travelling: 2 countries over 7 nights, starting in Piraeus (Athens) and finishing in Santorini, with a new port waiting most mornings instead of airports and hotel check-ins.
The pacing runs to 6 port days and 1 day at sea — time to enjoy the ship between stops.
Good to know
- Best for
- Culture-led travellers
- Season
- Spring sailing
- Route
- Piraeus (Athens) → Santorini
- Pace
- 6 port days · 1 sea day
Day-by-Day Itinerary
Hover a day to find it on the map.
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The Ship
Your home for all 7 nights aboard MSC Orchestra — so you unpack once and wake up somewhere new each morning.
About This Cruise
The 7 Night Mediterranean is a 7-night one-way itinerary aboard MSC Orchestra. You board in Piraeus (Athens) and disembark in Santorini, calling at 6 ports across 2 countries along the way.
In sequence the voyage takes in Greece (Piraeus, Katakolon, Argostoli and 1 more), Italy (Bari) and Greece (Santorini, Santorini).
As a one-way sailing you'll fly into Piraeus (Athens) and home from Santorini, so it's worth checking the two gateways before you book. Longer hops are crossed on the 1 day at sea, keeping daylight hours for the ports. Sailing dates, cabin availability and fares vary by season — use Check Dates & Prices for live pricing, or call our team to talk through the options.