Panama Canal & Central America · Panama
Panama City
Panama City, Panama is a cruise port in the Panama Canal & Central America cruising region. Explore itineraries that call here and the ships that make the journey.
Explore cruisesYour time ashore
Explore Panama City
Find a cruise that includes Panama City, explore the ships that call here and use the map to plan your visit. This port is a homeport where cruises begin and end.
- Cruises calling
- 46
- Ships
- 23
- Cruise lines
- 12
Get your bearings
Where is Panama City?
Panama City
- Country
- Panama
- Cruising region
- Panama Canal & Central America
- Port type
- Homeport
Make it part of your voyage
Cruises & Panama City
Search departures or find an itinerary that calls here.
Sail from here
Search departures from Panama City
Cruises visiting here
Find Panama City in an itinerary
Cruises visiting Panama City
See all sailings →17 Night Panama Canal: LA to Miami Halloween
Virgin Voyages Brilliant Lady · 17 nights · Los Angeles → Miami · Day 12 · 9:00 AM–7:00 PM
16 Night Panama Canal - Ocean to Ocean
Princess Cruises Sapphire Princess · 16 nights · Fort Lauderdale → Los Angeles · Day 7 · 7:00 AM–6:00 PM
10 Night Classic Panama Canal Passage
Viking Mars · 10 nights · Panama City → Fort Lauderdale · Day 1
16 Night Inca & Panama Canal Discovery: Lima Overnight
Holland America Oosterdam · 16 nights · Fort Lauderdale → Montevideo · Day 5 · 9:00 PM–4:00 PM
10 Night Classic Panama Canal Passage
Viking Mars · 10 nights · Fort Lauderdale → Panama City · Day 11
10 Night Classic Panama Canal Passage
Viking Mars · 10 nights · Panama City → Palm Beach · Day 1
70 Night Grand South America & Antarctica Voyage
Holland America Zaandam · 70 nights · Round-trip Fort Lauderdale · Day 5 · 8:00 PM–5:00 PM
5 Night Rotterdam And Zeebrugge Short Break
Cunard Queen Anne · 5 nights · Round-trip Hamburg · Day 68
23 Night Panama Canal - Ocean to Ocean
Princess Cruises Coral Princess · 23 nights · Fort Lauderdale → Los Angeles · Day 6 · 7:00 AM–6:00 PM
14 Night Tropical Treasures Miami To Panama City
Regent Seven Seas Splendor · 14 nights · Miami → Moorea · Day 17 · 7:00 AM–5:00 PM
11 Night Cruise Eastern Caribbean: St.Kitts, Antigua & Martinique
Azamara Journey · 11 nights · Round-trip Miami · Day 68 · 9:30 AM–10:00 PM
28 Night Canal To Coral Reefs Panama City To Papeete (Tahiti)
Regent Seven Seas Splendor · 28 nights · Panama City → Moorea · Day 1 · Departs 7:00 PM
15 Night Panama Canal
Holland America Zuiderdam · 15 nights · San Diego → Miami · Day 10 · 5:00 PM–4:00 AM
16 Night Panama Canal from San Diego to Miami: Mexico & Colombia
Norwegian Star · 16 nights · San Diego → Miami · Day 11 · 7:00 AM–10:00 PM
40 Night Cruise Buenos Aires To Miami Grand Voyage
Azamara Journey · 40 nights · Montevideo → Miami · Day 34 · 9:30 AM–10:00 PM
18 Night Valparaiso To Miami, Fl
Silversea Silver Nova · 18 nights · Valparaiso → Miami · Day 13 · 8:00 AM–11:59 PM
15 Night South America Pathways: Chilean Fjords & Glaciers
Holland America Oosterdam · 15 nights · Montevideo → Fort Lauderdale · Day 27 · 10:00 AM–5:00 AM
22 Night Journey To The Amazon Panama City To Panama City
Regent Seven Seas Grandeur · 22 nights · Round-trip Panama City · Day 1 · Departs 5:00 PM
19 Night Cruise Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel
Azamara Journey · 19 nights · San Antonio → Arica · Day 13 · 9:30 AM–10:00 PM
16 Night Machu Picchu & Mayan Ruins Lima (Callao) To Miami
Regent Seven Seas Mariner · 16 nights · Salaverry (Trujillo) → Miami · Day 9 · 1:00 PM–10:00 PM
16 Night Inca & Panama Canal Discovery: Lima Overnight
Holland America Oosterdam · 16 nights · San Antonio → Fort Lauderdale · Day 12 · 10:00 AM–5:00 AM
16 Night Panama Canal - Ocean to Ocean
Princess Cruises Crown Princess · 16 nights · Fort Lauderdale → Los Angeles · Day 7 · 7:00 AM–6:00 PM
5 Night Pacific Coastal
Princess Cruises Coral Princess · 5 nights · Vancouver → New York City · Day 16 · 7:00 AM–9:00 PM
18 Night Panama Canal - Ocean to Ocean
Princess Cruises Coral Princess · 18 nights · Los Angeles → New York City · Day 11 · 7:00 AM–9:00 PM
16 Night Panama Canal - Ocean To Ocean
Princess Cruises Star Princess · 16 nights · Los Angeles → Port Canaveral · Day 11 · 7:00 AM–9:00 PM
17 Night Panama Canala from Los Angeles to Miami: Mexico & Bahamas
Norwegian Bliss · 17 nights · Los Angeles → Miami · Day 11 · 7:00 AM–9:00 PM
16 Night Panama Canal - Ocean to Ocean
Princess Cruises Emerald Princess · 16 nights · Los Angeles → Fort Lauderdale · Day 11 · 7:00 AM–9:00 PM
10 Night Classic Panama Canal Passage
Viking Mars · 10 nights · Panama City → Fort Lauderdale · Day 1
9 Night Cruise Southern Caribbean Holiday Cruise: Aruba, Bonaire & Cura�Ao
Azamara Quest · 9 nights · Bridgetown → Valparaiso · Day 18
115 Night World Cruise
MSC Magnifica · 115 nights · Round-trip Civitavecchia (Rome) · Day 21 · 6:00 AM–8:00 PM
10 Night Miami, Fl To Cartagena
Silversea Silver Shadow · 10 nights · Miami → Villefranche (Nice) · Day 13 · 7:00 PM–6:00 PM
10 Night Classic Panama Canal Passage
Viking Mars · 10 nights · Fort Lauderdale → Panama City · Day 11
10 Night Central American Seas Miami to Panama City
Oceania Marina · 10 nights · Round-trip Miami · Day 11 · Arrives 8:00 AM
115 Night World Cruise
MSC Magnifica · 115 nights · Round-trip Barcelona · Day 18 · 6:00 AM–8:00 PM
112 Night Cape To Cape World Cruise: Miami To Lisbon
Seabourn Quest · 112 nights · Miami → Southampton · Day 5 · 9:00 PM–4:00 PM
Past sailings (5)
6 Night Pacific Wine Country
Princess Cruises Coral Princess · 6 nights · Vancouver → Fort Lauderdale · Day 17 · 7:00 AM–9:00 PM
7 Night Pacific Wine Country
Princess Cruises Star Princess · 7 nights · Victoria → Fort Lauderdale · Day 18 · 7:00 AM–9:00 PM
16 Night Panama Canal - Ocean to Ocean
Princess Cruises Coral Princess · 16 nights · Los Angeles → Fort Lauderdale · Day 11 · 7:00 AM–9:00 PM
16 Night Panama Canal - Ocean to Ocean
Princess Cruises Star Princess · 16 nights · Los Angeles → Fort Lauderdale · Day 11 · 7:00 AM–9:00 PM
16 Night Panama Canal from Los Angeles to Miami: Mexico & Jamaica
Norwegian Bliss · 16 nights · Los Angeles → New York City · Day 11 · 7:00 AM–9:00 PM
46 sailings call here. Search all itineraries →